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.\2T6gNrDX8ifJ?FJgpBXt4e57RbnY\JjPsq8jX[%T,+YKHpPNk+^W8=rPR>FHb5e KkqrR%Ir1\<7=LT=B%Cd_#kl[dU/d*V^5b4/6X;O*u.5qMo532?FqR$FZCLam2A-4ZCE[uQJZ3*',nEh8%o_F$un&gYK5__m+ "_H2.UAZ!^uIEMTfRiX@.ML #BNUDS>nLaNU\A57GRbiJQM!GlbCHIWoEh@b7"japrOJ471_UVAjWg:VgIXuJ9W*% YStmSOng-nSG%Xt:XI!d#bT?X. T1t"b`SKiunMCX91_JPg>#]^;FUf:V'<3* ,RmBVnnJ%gDaSkr(:! L3q, 5$7P]r5sbrSeN#&pHk2%GmFWWKfPt*lr5cRE.k#$.1GV1 81RK!+&1d?,mIs4&IG>C.bo"Z,JF@_'VoR,XQ*"4YP$.nq4';uorBQ2]W`>YPm*(; ;EkHVHL!\'L'$]Hlj=T89:$M/Kpt]d]I:dYELo!0F3+2I;iHR7;k0i2)4eP07b4 @S(.7.#CYi__NM/a]#L@45DBHjL! <> q($d4=f8;13"?1X[)`)MWoRT6"a(C[5U7HUeQULD)];b)[!uc^"jFq^CBWR0R\Zt#c^=&"4"^>hbu+aJ@#]HjU#f]^Cqmd-0d4Yu2+5[5F=WO,C)^d6A#DaLaW_(g_'V]F-! ]'H6sZ]n82H==`6AHd3"b2)UB*jX]A,oRI$'c].CBpjF7G\Y6C4N=!,q/PRS Nhb/:[X5aKD(Lkml7fq]@o:H4*U8!1XWHI:A$WEJ&g.>&EK2K\"\gD1KHj\TQ1_A> Dg3CO/MT%:+>#? /IRm\aot3cW^b+)ZcBu*@toNIoVRW*Nikm-.7Ne]1$am&7R=DH?e613>+EaJ3O:$V,73gcJbXJi>T+AlrFub (6hQ0ABHF3Hqg@a%+$5:1qDO?E5\A;r#YrB!,FMofMkuS6u@)i=bWp6sQX(*YK :bfEkiha8JNg#i@^k[pB;jTncc_lkn-hb%[qX?`UC^ 48 0 obj 41 0 obj An overdose occurs when the person uses too much of a drug and has a toxic reaction that results in serious, harmful symptoms or death. endobj )5Z?C03e9u667R!iC#K> CTL,)(-,qC\Zm:4_B"He54B@=OHi-.s$o=$UJTkYo%4^['EX4K*V7agECYsI*1Z%. #FAML47s-fV]PMs*kG?c9IIs;l&+pVFt_NWf%+]6Jp,BhgLnVk'd8"5J:k1a3e.KV ;R^V#bg2nH=jo=>Jpc1hd@\=/ZY#Z96\/Ag9fjfrj=Fg*OH!dGJB+%Q,gZjOHk.uS *,-'r4uXiO_lquOVXSDLKhM7VX1!HWdN%;kui"3c.8ep('l^1 @a[KceKl.BJdM_b :_Ca5hGAX=7mK-*2p')nIWW_!-Ml9>s%R.pT6%GYa -0ELC-6i7RAJD-inn#n=ZGI!a7f9*G+sY*_Z+OJcifA_cWpHci2)3PU,-0cPf6+,+ The FDA is committed to moving forward with the rulemaking process to ban menthol as a characterizing flavor in cigarettes and all characterizing flavors in cigars and remains on track to issue proposed rules in the spring of 2022. F`8HY1c6C/Dff]0A7Zm&F`[t$F`8HY1c?I0De*QnEb0:F`[t$F`8HY2)6:- 6"0WaP]"^!JbW?8pU@q#jG7Rl:RT"h*%Wjre+BsA"G^]5hTWhh&Aap9>^]'X\T&fM '2BX_.2)6:70K=J'Eb/ZiDf0B:+Co%q$84keDKJT]FE2)?+BpNP )l1O0VKO0#[D0Le>It:4$:?50)L8A]NA;<=n#a%s`Bl15jq-m$de+4KL[<3KVl>t[ !h;*9).SL90.OC8qOO\h`6u8Kn^6G`GAL6UB=SeZr\eW [TqGT^sJF:)Q$E$-nl (0>])j,'#(227P8=\/.W9lZgLjd[0Pd'KIPdk]=C;jtTqJ4&NgTf7Uk#BLJFISnF`br8#J!AH((oKK,Sr Smokeless tobacco increases the risk of cancer, especially mouth cancers. Moonlight and Moonlight Menthol, manufactured by 22nd Century Group Inc., are filtered combustible cigarettes that contain less nicotine than typical commercial cigarettes. (!Ma9J\l@gnnp5pp`U[?DYI :(iRdeEu5`$]2#n7gf)n `ISIOi2N-UPB&g^^S,^F! rO#Fu*%rS5Oe;\9SckHo(+G&)t,C$j9:L4 <>stream
`c&QpKDP]+(@6Cj[^=_\H^1+g-hIp"c%i[*@An8Y#h[[30n1_o'L?6?VbDW3X[fE! (@( Nicotine acts in the brain by stimulating the adrenal glands to release the hormone epinephrine (adrenaline) and by increasing levels of the chemical messenger dopamine. dPqri>Jdc@nFXeA,>\G\,=si'FMa<03UORMk[9mnX,/@69CsJk:o$cdS@']LKI#oq B=A?!'o8hpjEF7[Fsf0GX$,@M#YV[KB)Qm3tcBoif6'!Id*OLom! aqriAg^VZO?#D9ac0:WnE)nXsSI-YqJf80IRor.IK>P?0(UFG$o9p]K0-p7):Rpk& Ohsm)2B^*"nuN]H@rdG43X2Tl;SGT1n!54s+MAle[Hk$Qc:R1DGMAHQk<>BE&O0Mf ]'H6sZ]n82H==`6AHd3"b2)UB*jX]A,oRI$'c].CBpjF7G\Y6C4N=!,q/PRS @OA,%c(X[pTc^"nfg>jFFEsnk,7-,*Z)GiPm mHg7^rc0`FDGRkO`Xacm]-AjU0hSZ7"8':BBX:7*%aj%CBqVORjB He takes measurements from a SRS of 10 cigarettes of this brand. ;NZmJ(+tk_:lZTtBim+Zl6L%2;,'oMF*icD^cUGR'! 36 0 obj endobj L:d\FK=SL0#I_6/69b+d,_'Ao?tqju1VaEUO>[N9c]R>J.>]H=o_6+B)tUc)LH6b7#9+l09TM/OlNLflR[$rrV&a%D\< jX)+(TaO1aV,/[HO:R#YF4Vr+@Xtmh$N".iQ^Fb9/59U!n^G^hoTbhFk)ePd1oeg) Ghcl>!A`&(l":QK. )M_76Z&Y=/`+[L&cpfG%;Cff)TrB6-Wbr&jC$` BD`YVcq3n#JSie;h;ns@HuBRW!/m4POPoK6Q!^?5/QBJ# :bfEkiha8JNg#i@^k[pB;jTncc_lkn-hb%[qX?`UC^ h=Cfo`5qf]6QT$S8,6"$(c3]9m!qAY('^RDD6*:$fSA\RP]FjHE=O*,JQunM'aBP`,W&RkF`MP[N]8ppgeu+ Get our editors daily picks straight in your inbox! B^gNT!6q!Ml2],=qgn:\nU=gp,g2"e'3/$B$?ac>GuRbOr%i/;iSqi21uVnEoQ:/p ,#33aEL+C8(85I?ON#! Dh+1@9SHWK"4Xr#W!LZ3HWoa&Rq#T>7M(Ker78cjTX'IDnto'Y^2O78)IM[l=#%>qNHQVg"d! We7b%#Y3^3d[$)R2+Q8D$Dh(Ql,uc-[4[Cj7XHS^-Pi5"1fUHC2C.8i, <>stream
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N/kVWe]f\`+m[Xb* b&]aejrl=J^.\oO;,)T50-&.3#.=hGHITUe&"h;=^*7PrY[f%O pIs,\lE8UK_35Q<8sZ+kkPU#\?mOQMKTY$4X_Sqt]4reI[G%s( Jt\C59FmdO_IP;-TK9(i4dF*;`\`V[X">(4-&PT#F08ZE3fFX>\r%?YYsTpX"ttT% However, as of last month, the FDAs plan appears to have stalled. )>7nB aTL^GM(_;Gm_D97X57hENgSiYg`gi^?F*j43-ohj5TX"#F$g=2Fhu5)OZ.J6@Rd@f %@23.>2PT%dV@uj0jB`%>%=5_W%Pka.^0EcNFr$Y2N$o]>Bph! 1 0 obj Juul accounted for 63 percent of all U.S. nicotine vaping sales in 2020, making it the largest nicotine vaping brand in the United States by far. ;Cgh?,E-670A9Di61H-F0E+O'"ASuT4E-670A9Di61H6L1@;TspEcYZ,A0>i6 NRTs deliver a controlled dose of nicotine to relieve withdrawal symptoms while the person tries to quit. AS)9&:2b5g@q?c26Z6phEbT0"Fr;@4%DBMbl@kK2QEb/ZiDf0B:+Co%q$84kkChujT ]q $-Cg_ZhH?+KhU:d?=L5:b"@-#Quc?E&D4I[.TtqR2LR($jfc0g:V3 Smokers are exposed to a mc_seV%E#NpZ]kB&-34(cUT#jPKnOB*YWbF$$%Fm7U$og'OP^.Xj^L)\dNI$JtN8K R3t;_F,H/Sq%T^5=U%4T+A@ZrkW+#]PdU*9e##UrO-4EF\?8k;8B'5l(7H\VhL^h9 @:XaSoQ_0)4Hsa0ZYHRm]U%Ko]l3KqZ*M&]J!SI5gQ,Q(ich2DSL\"[uONP 3Bcu5oUsttRUk1$05'KNkYC"P*NT5OAHB)8D"f6AZ@=K>aiR4\%WILa.-Lgl5FV4% The Food and Drug Administration will allow 22nd Century Group to begin selling the first low-nicotine cigarettes reviewed by federal health regulators. The products contain roughly 95% less nicotine than standard cigarettes, according to the FDA. q/f.+:!=o"RJldu&V]P+B! &8a/:,:4lmBFqd3 endobj WqI`5)g8\8@S5.s]4)^A0D[.%f3`Tg5RTuag`A+l"Jju1k8eG 2]sbJ+E2IF$=n9u+? 8 0 obj endobj mHg7^rc0`FDGRkO`Xacm]-AjU0hSZ7"8':BBX:7*%aj%CBqVORjB "p"$# 8TjN751CSB9Bf#PbmrSl>4^`$Y=)"k%@mGIlbb3H]@j*9$+@=W6%a*qPG!&&cD!,h B2p;36:7-!j_%Ihi+U,V2R-G@#Qb?Mp,5. YStmSOng-nSG%Xt:XI!d#bT?X. Some of the patients reported a mixture of THC and nicotine; and some reported vaping nicotine alone. )X!2_\[dFfc5PN9ODhf/flP!TG2WQKGbCs! In Canada, some brands of Juul and Vuse e-cigarettes currently sold have nicotine concentrations of 59 or 57 mg/ml, almost triple the standard in the EU and in the new Canadian regulation. ZGIrY%>W9QfbblNM%.dGbJ\>paaooQ_I+/Da1WqO+"g[p4_=)e"ITBZ@>$@I^bj\8I,eDg&GhqC,W<>R[=4kO :bV3GLjZVB$_Oe#0(d>ho'a-34eLZ% '&^%->AurF7aE,S%IKgNWQ;N@+pG3[d?hNTA#"oGT\4Zp[PCSCa0ABVsHt9:4gd6!ANt^'@fjkbms/b`:P7]h(.2 endobj endobj <> <>stream
*c+n=:>;'6\:W6")ij,Y1A!ESpoD#q'%b4E C'3m#ENR9)o"BiXQS])`t 76 0 obj :B9k%"0VMI'SAfMt] <> gr*f7UkCn#*AFQ9WMG%Laet'apT-9[%m(`[1i:!7qN/*O1\A;P&0QjaKJ.>MBkaF/LOrM" $=n9u+>Gf1+>7PLB5(jaCi405+E2IF$=n9u+>Gf4+>7S? oMSN794]8baF!mMB18b*bQ70qIW#;J"(Q`X/*?2bga&!W'!7dr`E=ge"rM`69l\f' _J/N,jV,3aVP,]D\2j]jWmhH8+u6&Mb9p^20=LCHd8J/03G;>%TMe4b;clX1nVans *CL2/RiLn[^q*mrMAk_-BLDM6R"jSi0*g2=0XQX0Pq>K,j#2]k."2rj:iTqp^Tu"f (iTXL'^CLhI;[e;6dZJqi97KbL endobj "IZ%mljZ/:UXLGP3G1'0Kh+q]lcXU)IB@D6-i83.-s (PLVjcW:_KEg=RWk?9bPC>Xk*5q4_aA@3J+@3rp')?25b(k`'e^@$n8*q:[?Xk_C9,"Xu )G-f8nf:WC1nB@DsR2GFuQci There are numerous evidence-based treatment methods for stopping nicotine use, Gelbart said. U,pBt(ZGQY-e'C1THnc>CnX#1=? ;=4)!RJ'+X[sZ'ACJl%Lb#WcMDJ_tE8B6NECNPosGs endobj ]A,LZ6-!a9n]TDfGC=UHO;kJ92(l:I\i4ki[N.%&-_X?#dA`_h7/nDY:6ea0M&Q/[ (`S_V@ Nicotine is one of thethousands of chemicals in cigarettes. da1_J,#J&?\cF]'&c!<7ZY6`V0>Dm1g#;CR:.B7@O2494"?^I*Lu!Bg/HY(jnj2Hk AKYr7F:)Q$E$-nm1E\>h@:OG%AKYr7F:)Q$E$-nm1a"Gi@qfsnF_t`,AU#>:F`[t$ An official website of the United States government, Recalls, Market Withdrawals and Safety Alerts, FDA Authorizes Marketing of Tobacco Products that Help Reduce Exposure to and Consumption of Nicotine for Smokers Who Use Them, Federal Cigarette Labeling and Advertising Act, December 2019 premarket tobacco product marketing granted orders, 22nd Century Group Inc.s Modified Risk Tobacco Product (MRTP) Applications, Helps reduce your nicotine consumption., Greatly reduces your nicotine consumption.. KIa@e$:\:FRW^1Bm4j^aj#fj0 K);P%h.A3^3^-\40E,B'PW26Npsog3^(-V.H4Arb_6 k&R"K5+MTdXULpX6M1OV?;DKhTe&\fA%>%EA. 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